Mario Miranda started his career in an advertising studio, where he worked for four years, before taking up cartooning full-time. He got his first break as a cartoonist with The Illustrated Weekly of India which published a few of his works. His drawings & cartoons also brought him an offer to work at the Current magazine. A year later, the Times of India offered him a slot, even though they had rejected him at first. Thereafter, his creations, such as Miss Nimbupani and Miss Fonseca, appeared on a regular basis in Femina, Economic Times, and The Illustrated Weekly of India.